Advanced hormone panel
Is this test for me?
How it works
options works for you
What we analyse
Luteinising Hormone (LH) is produced by the pituitary gland and is important for male and female fertility. It governs the female menstrual cycle, peaking before ovulation, while in male bodies, it stimulates the production of testosterone.
Oestradiol is a female steroid hormone, produced in the ovaries, and to a much lesser extent, in the male testes. It is the strongest of three oestrogens and is responsible for the female reproductive system as well as the growth of breast tissue and bone thickness. In pre-menopause, oestradiol levels vary throughout the monthly cycle, peaking at ovulation. Female oestradiol levels decline with age, culminating with menopause when the ovaries stop producing eggs. Low oestradiol can cause many symptoms associated with menopause, including hot flushes, night sweats and mood swings. Low oestradiol can also cause osteoporosis.
Testosterone is a hormone that causes male characteristics. In male bodies, it helps to regulate the sex drive and has a role in controlling bone mass, fat distribution, muscle mass, strength and the production of red blood cells and sperm. Testosterone is produced in the male testes, and in much smaller amounts, in the female ovaries. Male testosterone levels naturally decline after the age of 30, although lower-than-normal levels can occur at any age, causing low libido, erectile dysfunction, difficulty in gaining and maintaining muscle mass, and lack of energy. Although female bodies have much lower amounts of testosterone, it is important for many of the same reasons, playing a role in libido, the distribution of muscle and fat and the formation of red blood cells. All laboratories will slightly differ in the reference ranges they apply because they are based on the population they are testing. The normal range is set so that 95% of men will fall into it. For greater consistency, we use the guidance from the British Society for Sexual Medicine (BSSM) which advises that low testosterone can be diagnosed when levels are consistently below 8 nmol/L and that levels below 12 nmol/L could also be considered low, especially in men who also report symptoms of low testosterone, or who have low levels of free testosterone.
Follicle Stimulating Hormone (FSH) is produced in the pituitary gland and is important for the production of eggs by the ovaries and the production of sperm by the testes. In the first half of the menstrual cycle, FSH stimulates the enlargement of the follicles in the ovaries. Each of these follicles will help to increase oestradiol levels. One follicle will become dominant and will be released by the ovary (ovulation), after which follicle-stimulating hormone levels drop during the second half of the menstrual cycle. In male bodies, FSH acts on the seminiferous tubules of the testes where it stimulates immature sperm cells to develop into mature sperm.
Prolactin is a hormone which is produced in the pituitary gland and plays a role in reproductive health. Its primary purpose is to stimulate milk production after childbirth, therefore during pregnancy and breastfeeding, prolactin levels can soar.
The free androgen index (FAI) is a calculation used to determine the amount of testosterone which is free (unbound) in the bloodstream. Most testosterone is bound to proteins – sex-hormone-binding globulin and albumin – and is not available to interact with the body's cells. The FAI is a calculation based on the ratio of testosterone and SHBG and is a measure of the amount of testosterone that is available to act on the body's tissues. The free androgen index is used in women to assess the likelihood of polycystic ovary syndrome. In men, free testosterone gives a better indication of testosterone status.
Most of the sex hormones - testosterone, oestrogen and dihydrotestosterone (DHT) - found in your blood are bound to Sex Hormone Binding Globulin (SHBG) which means that they are unavailable to your cells. Measuring the level of SHBG in your blood gives important information about your levels of free or unbound hormones which are biologically active and available for use.
This test looks for antibodies to thyroglobulin, a protein which is specific to the thyroid gland. Under normal circumstances it does not enter the bloodstream, but if your thyroid is inflamed or under attack from the body's own immune system, then thyroglobulin can be secreted and antibodies detected.Most cases of thyroid disease are caused by an autoimmune condition where the thyroid gland is attacked by the body's own immune system. This can cause the thyroid gland to produce more thyroid hormone (as in the case of Graves' disease) or to produce less as the cells in the thyroid gland are gradually destroyed (as in the case of Hashimoto's thyroiditis).
Thyroid peroxidase is an enzyme which is produced in the thyroid gland and is important for converting T4 to the biologically active T3. This test looks for antibodies to thyroid peroxidase which indicates that the body's immune system is attacking the thyroid gland and impairing its function.
Thyroxine (T4) is one of two hormones produced by the thyroid gland. It works to speed up the rate of your metabolism. Most T4 is bound to carrier proteins in the blood, but it is only the free, or unbound T4 that is active in the body, which is measured in this test.
Triiodothyronine (T3) is the more active of the two thyroid hormones produced by the thyroid gland. Most T3 is bound to protein in the blood. Free T3 measures the level of T3 that is free, or unbound to protein, and is available to regulate metabolism.
The thyroid is a gland at the base of your neck responsible for a number of metabolic processes, including energy expenditure, cardiac function, muscle physiology and substrate turnover. Disturbances in your thyroid function can lead to excess hormone levels (overactive) or diminished levels (underactive), both of which can lead to a decrease in athletic performance.Thyroid Stimulating Hormone (TSH) is produced by the pituitary gland and stimulates the thyroid gland to produce the two thyroid hormones thyroxine (T4) and triiodothyronine (T3).Thyroid hormone production is part of a neuroendocrine cascade. It starts in the hypothalamus with the release of thyrotropin releasing hormone (TRH), which triggers the pituitary gland to produce thyroid stimulating hormone (TSH). This binds to cells in the thyroid gland to release the hormones T3 and T4 (thyroxine). T4 is also converted into T3 (the more active thyroid hormone) at peripheral tissues. It is these hormones which essentially control the metabolism around your body. All these levels are normally held in tight balance through negative feedback loops. Abnormal thyroid function can manifest by over-secretion or under-secreting the thyroid hormones. Very often there is an autoimmune component to these conditions and we can often see this by looking at your thyroid antibodies in more advanced thyroid tests.
What you’ll get
- A 12-parameter blood test
- Venous blood sample or finger-prick test
- An interactive dashboard and the bioniq app to monitor your metrics and progress
- Comments from a General Practitioner regarding your results
- Additional services
- At-home blood test £55
- Individual nutrition consultation £50
Get ready for the test
- Please make sure to take your test in the morning
- If you are taking a T3 containing medication, take your test in the hour prior to your dose of medication
- Take this test between days 2 and 5 of your period. It can be taken at any time if you are not having periods
- Do not take biotin supplements for 2 days prior to this test. If you are taking prescribed biotin, consult with your medical professional prior to taking the test
- HRT and the contraceptive pill can affect the results of this test, taking the test during a break from these will give more accurate results
- Avoid taking a finger-prick sample from a finger used to handle hormone-gels or hormone-pessaries in the past 4 weeks
- Avoid heavy exercise and eating meat-rich meals for 48 hours before your test
- You should take this test before you take any vitamin or mineral supplements
- If you want a more accurate result of your natural hormone status then this test should be taken at least 12 weeks after stopping any hormone replacement or contraceptive pill, implant or hormone IUD
- If you are premenopausal and do not wish to become pregnant then please make sure that you use an alternative non-hormonal form of contraception
- If you have not been through the menopause then we suggest waiting until your periods have re-established a regular cycle (for you) before taking this test
Our partnering clinics
Track your health on the go
- Results archiveAccess information about your tests at any time to use for yourself or share with your healthcare provider
- Health progressTrack how your health metrics change using infographics and easy-to-understand charts
To collect your blood sample, you can choose either
• At-home sampling by a qualified nurse for an additional fee
• Visiting a Medichecks clinic
• Ordering a finger-prick test kit and posting the sample yourself
Unfortunately, not at the moment. However, we aim to provide a better experience and are currently increasing booking transparency.
After successful payment, your order will be placed. Our client service sends the data to a partner clinic which assigns a nurse in your area. The nurse will contact you within 2 working days to arrange an appointment.
You will receive a prepaid envelope to post your blood sample back to the lab. After the test, your nurse may offer to drop it in the post. Please ensure that your sample is posted on the same day as your test, as soon as possible.
The study shows that there was a significant improvement of the iron plasma and total blood level as well as the ferritin level after taking bioniq.